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10.02.25 | Sage Advice®

Vaccines and Brain Health: Emerging Evidence on Dementia Risk Reduction

When we think about vaccines, our minds often go to protection against the flu, pneumonia, or shingles—illnesses that can be especially concerning for older adults. But a growing body of research suggests vaccines may do more than shield us from infections. They might also play an unexpected role in lowering the risk of dementia. While this is not yet definitive, the evidence is intriguing—and worth sharing.

The Science Emerging
In recent years, several studies have found a potential link between common vaccines and a reduced risk of cognitive decline. For example, older adults who received flu, pneumonia, or shingles vaccines were found to have a lower incidence of Alzheimer’s disease compared to those who did not. Scientists believe that vaccines may stimulate the immune system in a way that helps clear harmful proteins in the brain, or reduce harmful inflammation—both of which are associated with dementia.

While the exact mechanisms are still being studied, the evidence is promising: these everyday preventive measures may also provide long-term protection for the brain.

Why This Matters
Dementia, including Alzheimer’s disease, affects millions of people worldwide and has profound impacts on families and communities. At Sage Collective®, we emphasize the importance of vibrant living—taking proactive steps to nurture not just our bodies, but our minds and spirits. If something as simple as a routine vaccine can contribute to brain health, it underscores the power of prevention and the interconnectedness of our health choices.

A Broader View of Wellness
Vaccination is just one piece of a larger wellness puzzle. At Sage Collective®, we encourage a holistic approach to healthy aging: nourishing meals, regular physical activity, meaningful social connection, spiritual enrichment, and ongoing learning. Adding vaccine awareness into this mix expands our toolkit for living with vitality and resilience.

Possible Mechanisms
Researchers are still piecing together why vaccines might have this effect. Some leading theories include:

  1. Reduced systemic and neuroinflammation – Fewer infections means fewer inflammatory cascades that can damage neurons.
  2. Immune system “training” – Vaccines may recalibrate the immune system to respond better to harmful proteins in the brain.
  3. Prevention of viral reactivation – Shingles vaccines prevent reactivation of varicella-zoster virus, which may reduce neural damage.
  4. Adjuvant effects – Some vaccines, especially newer ones like Shingrix and RSV, include immune-boosting adjuvants that may have additional protective benefits.

Looking Ahead
It’s important to note that research is ongoing, and vaccines are not a guarantee against dementia. But the possibility that they may reduce risk offers hope and reinforces the value of staying up to date with recommended immunizations.

As scientists continue to explore this exciting connection, we can continue doing what we know supports longevity and joy: making intentional choices that keep us strong, engaged, and connected.

Key Studies & Findings
Here are several notable research efforts that have investigated associations between vaccination and reduced dementia or Alzheimer’s disease (AD) risk:

Influenza (Flu) Vaccination

  • Bukhbinder et al., 2022: A nationwide U.S. study found that flu vaccination was linked to a lower risk of Alzheimer’s disease in adults aged 65+.
  • Zhao et al., 2024 (UK Biobank): Repeated flu vaccinations correlated with progressively lower dementia risk, showing a clear dose–response relationship.
  • Yang et al., 2025 Meta-analysis: Involving nearly 10 million participants, this study found the strongest protective effect in high-risk populations (e.g. vascular disease, COPD).

Pneumococcal Vaccination

  • Huo et al., 2024: Using the IBM MarketScan database, researchers found pneumococcal vaccination was linked to a 63% lower odds of Alzheimer’s disease.
  • Duke University Cardiovascular Health Study: Vaccination between ages 65–75 was associated with a 25–30% reduction in Alzheimer’s risk.

Shingles (Herpes Zoster) Vaccination

  • Harris et al., 2023: Shingles vaccination was associated with about a 25% lower Alzheimer’s risk in adults 65+.
  • Taquet et al., 2024 (Nature Medicine): The Shingrix vaccine was linked to a delay in dementia onset—about 164 additional dementia-free days.
  • Welsh Natural Experiment, 2025: Those eligible for shingles vaccination (based on birthdate rules) had a 20% lower incidence of dementia over seven years.

Tdap / Td (Tetanus, Diphtheria, Pertussis) Vaccination

  • Harris et al., 2023: The same large cohort study found that Tdap/Td vaccination was associated with a ~30% lower risk of Alzheimer’s disease.
  • Taquet et al., 2024 (Nature Medicine): Found a smaller but measurable protective effect of Tdap, with vaccinated individuals experiencing modest delays in dementia onset.

RSV (Respiratory Syncytial Virus) Vaccination

  • Oxford University, 2024: Recipients of the new Arexvy RSV vaccine showed a 29% reduction in dementia diagnoses over an 18-month period.

Caveats & Open Questions
It’s important to note:

  • Most findings are observational, not proof of causation.
  • Healthier adults may be more likely to get vaccinated, creating “healthy-user bias.”
  • Dementia is often underdiagnosed or misclassified, which may affect results.
  • Effect sizes vary: shingles and pneumococcal vaccines seem to show stronger associations than flu or Tdap, but evidence is still emerging.

What We Can Do Today
While the science is evolving, the message is clear:

  • Stay up to date with recommended vaccinations (flu, pneumococcal, shingles, Tdap boosters, RSV if eligible).
  • Consider that these vaccines may offer double protection—against infections and potentially against cognitive decline.
  • Continue investing in a holistic approach to brain health: regular exercise, nutritious food, social engagement, spiritual well-being, and lifelong learning.

As we embrace choices that nurture body, mind, and spirit, vaccines may now be one more tool in the toolkit for a longer, healthier, and more joyful life.

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09.18.25 | Community

Q&A with Olivia Matongo, Alzheimer’s Association® on Brain Health, Equity, and Community

Sage Collective® and the Alzheimer’s Association® share a powerful common ground: helping older adults live vibrantly with knowledge, connection, and care. Ahead of our Facebook Live conversation with Olivia Matongo, Vice President of the Alzheimer’s Association® Illinois Chapter on September 23, 2025 at 7:00PM CT, we sat down with Olivia about a number of subjects, including how to make brain-healthy living more accessible, equitable, and actionable for our community.

In your role, what does a “good day” look like—and who benefits most from your work?
My team leads community outreach and engagement—we’re the ones executing the mission in the field. That means raising awareness about the disease and about our resources, building relationships with community leaders and organizations, and making sure people who are struggling can access care and support.

How did the relationship with Sage Collective® come to be?
We met at a community meeting and started talking about ways to partner. After follow-up conversations, we landed on doing a session focused on brain health—sharing who we are, what we do, and how we can support Sage Collective®’s community.

Many people ask how to distinguish normal, age-related memory lapses from early warning signs of Alzheimer’s. How do you explain the difference?
Normal aging isn’t disruptive—you might occasionally forget something and then remember it later. Dementia involves memory loss that interferes with daily life, like getting lost on a familiar route or struggling with tasks you used to manage easily. It affects the individual and those around them as loved ones notice changes and step in with more support.

We’re hearing more about new blood tests entering the diagnostic toolkit. What should families know?
Diagnosis is never one single test—clinicians use a number of tools in the diagnostic process, including cognitive and behavioral assessments. Blood-based tools are emerging to help detect biomarkers associated with Alzheimer’s, which can make the path to answers less invasive and help families plan and prepare sooner in consultation with their clinicians.

What daily habits do you encourage for better brain health?
At the Alzheimer’s Association®, our public health team recently launched “10 Healthy Habits for Your Brain” grounded in research. Highlights include moving your body, not smoking, managing blood pressure and diabetes, getting enough sleep, keeping your brain learning new things, and following the MIND diet (leafy greens, berries, nuts, lean proteins, and less butter, cheese, and red meat). Doing several of these together can meaningfully reduce risk over time.

Sage Collective®’s “9 Ways of Vibrant Living” align closely with your recommendations.
Exactly. Engagement and purpose are powerful. When partners like Sage Collective®help us reach people with practical, everyday ways to take care of brain and body, the impact multiplies.

How is the Alzheimer’s Association® building trust and access in communities that have been underserved?
We’ve invested for years in focused DEI efforts—partnering with organizations already rooted in Black, Brown, and rural communities. In Chicago, for example, we co-create annual conferences with community planning committees—one on the South Side centered on African American communities and one on the West Side centered on Hispanic communities—so that education, resources, and support truly reflect community needs.

What does a strong partnership with Sage Collective® look like to you?
Access and trust. Being invited in to educate and support your community is huge—and it’s reciprocal. We also ask, “How can we serve Sage Collective®’s goals?” As our organizations continue talking, the partnership can evolve in ways that make sense for both missions.

Join us live
Don’t miss our Facebook Live with the Sage Collective® team and Olivia Matongo from the Alzheimer’s Association®, taking place on Tuesday, September 23rd at 7 PM CT/8 PM ET. We’ll dig deeper into early signs, new diagnostic tools, everyday prevention, and community resources. Bring your questions—and invite a friend or care partner. Go to the Sage Collective® website to reserve your spot!

 

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07.09.25 | Community

Beyond Fireworks: What the Fourth of July Can Still Teach Us

At Sage Collective®, we believe in embracing all of life’s complexities—holding joy and pain, celebration and struggle, side by side. As the 4th of July approaches, we invite our community to reflect on what this day promises, and also what it has yet to deliver. While many mark the occasion with picnics and fireworks, for older African Americans and others who have carried the weight of this country’s unfinished promises, the day can stir layered emotions.

Yes, the 4th of July commemorates the birth of American independence. But who has had access to that freedom—and who still struggles for it—remains an ongoing question. That’s why, each year, we take time not only to celebrate but to reflect. To ask: How do we, as a community rooted in cultural appreciation, vibrant living, and lifelong learning, make room for truth, memory, and forward movement?

Radical Hope in the Face of History
Hope, in the tradition of Black resistance, is not naïve optimism—it’s radical. It’s the kind of hope that propelled Frederick Douglass to demand accountability in 1852, when he asked, “What to the Slave is the Fourth of July?” It’s the kind of hope that allows us, even now, to hold pride in our cultural contributions while remaining critical of the structures that still need to change.

This radical hope is not passive; it’s grounded in the belief that change is possible, and that we are agents of that change, even in our later years. For the elders in our community—those who’ve marched, taught, raised generations, and kept our stories alive—this kind of hope is deeply earned.

The Right to Belong
Belonging is a powerful word. It is one thing to live in a country; it is another to feel of it. Many African Americans have wrestled with this duality for generations: loving a country that has not always loved them back. On July 4th, we reflect on what it means to both critique and claim. To declare that we are part of this nation’s fabric—not just as spectators to its history, but as authors of it.

At Sage Collective®, we believe aging deepens this sense of authorship. You’ve lived enough to know the contradictions. And you’ve lived enough to imagine something better.

Living with Complexity
Our elders teach us that holding complexity is a form of wisdom. You can grill with your family and still talk about injustice. You can sing along to a patriotic tune and still recognize its limits. You can love the idea of liberty while acknowledging that liberty has not yet been extended to all. At Sage Collective®, we hold space for all of it—the contradictions and the beauty.

Legacy and Citizenship
What does it mean to be an active citizen in your later years? It might mean voting. It might mean telling your story. It might mean mentoring, creating art, or simply refusing to be silent. We honor the idea that freedom isn’t something we receive once and for all—it’s something we continue to work for, together. Our elders’ participation in civic life is a gift that enriches communities and keeps the spirit of democracy alive.

This Fourth of July
So as we prepare to celebrate, we also remember. We honor the legacy of Frederick Douglass and so many others who demanded more of this country. We honor the legacy of our own lives—marked by resilience, creativity, and care. And we ask ourselves: What does freedom mean to me now?

At Sage Collective®, we believe it’s never too late to reflect, reimagine, and participate. This Fourth of July, let’s gather in all our truth—and step forward with radical hope.

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06.05.25 | Mental Wellbeing

It’s Never Too Late to Change Your Mind

At Sage Collective®, we believe that aging is an opportunity to discover new depths of your evolution. One of the most liberating truths we come to understand with time is this: it’s never too late to change your mind. Whether it’s a shift in perspective, a change in attitude towards people, or a complete reinvention of self, the ability to change your mind is not a weakness but a superpower.

Because we believe that vibrant living doesn’t mean standing still, it means challenging yourself to never stop  evolving.

Why Changing Your Mind Is a Strength, Not a Weakness
We are under the impression that age equates to certainty. We expect that once we arrive at this stage in our lives we should be able to know ourselves fully, have our set beliefs that do not change, and continue to live our life exactly the same. Although, we forget that the various life stages can be the reason for growth and change.

Changing your mind does not mean you are indecisive, it means you have enough security to reevaluate certain aspects of your life. Maybe you had an opinion years ago that caused you and someone you love to drift apart, or you thought someone was your soulmate but it turns out your story ran its course, or maybe the shirt you used to be obsessed with is hideous to you now. Whatever it may be, it is emotionally intelligent to always be questioning who you are and where you stand on certain decisions. Growth can be about sticking to your guns and advocating for what you believe in but it can also be the humble act of reassessing the past.

Real-Life Examples of Late-in-Life Pivots
Nina Simone is one powerful example. Known early in her career as a classically trained pianist and acclaimed jazz and blues singer, Simone experienced a profound shift after attending the 1961 American Society of African Culture conference in Lagos, Nigeria. The trip was life-changing. It awakened a deeper connection to her identity and political purpose. From that point on, she became a fierce voice for civil rights—performing at protest rallies, writing political anthems, and lending her artistry to the movement. She changed her mind about what her platform was for—and in doing so, changed the world.

Another remarkable story is that of Iyanla Vanzant, who initially rose to public attention as a lawyer and spiritual teacher. But her true transformation came later in life. After facing personal hardships, including the death of her daughter and the dissolution of her marriage, Vanzant stepped into her power as a healer. She became a celebrated author, spiritual counselor, and host of Iyanla: Fix My Life—a role she took on in her late 50s. Her shift wasn’t just a career pivot—it was a complete reimagining of how she would use her voice.

And consider Ron Finley, the South Central Los Angeles fashion designer who, in his 50s, decided to change his life—and his neighborhood—by planting vegetables in abandoned lots. Now known as the “Gangsta Gardener,” Finley’s work has become a movement, promoting food justice, sustainability, and self-reliance. He changed his mind about where power and purpose come from, and discovered a new form of activism in the soil beneath his feet.

Reframing Your Story
There are multiple ways to stay on your feet and remain open to change:

  • Stay curious: Read books, watch films, and listen to music that challenge your thinking.
  • Embrace dialogue: Spend time with people who see the world differently.
  • Reflect often: Journal without judgment, allowing space for evolving insights.

At Sage Collective®, we believe aging is about stepping fully into your own wisdom and embracing that wisdom. Changing your mind in your later years isn’t a sign that you’ve lost your way; it’s often proof that you’ve finally found it.

We as humans make the mistake of thinking that there is a final destination when, in reality, we never stop growing. Therefore, it is our responsibility to treat that evolution with mindful reflection and openness to the change it can inflict.

You’re never too old to change your mind—because you’re never too old to grow.

The Gangsta Gardener, Ron Finley. Credit: U.S. Embassy New Zealand (https://www.flickr.com/people/46907600@N02). Wikimedia Commons, licensed under the Creative Commons Attribution 2.0 Generic license.
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05.01.25 | Mental Wellbeing

Flipping the Script on Aging: Celebrating Older Americans Month 2025​

At Sage Collective®, we believe that aging is not an endpoint but a vibrant, evolving journey filled with wisdom, opportunity, and continued growth. Each May, Older Americans Month offers a national opportunity to celebrate these truths. In 2025, the Administration for Community Living (ACL) has selected a particularly powerful theme: “Flip the Script on Aging.” This year’s theme challenges outdated stereotypes and invites all of us to reshape the way we view aging — not as a period of decline, but as a dynamic, enriching phase of life.

Challenging Age-Related Stereotypes
For too long, societal perceptions of aging have been framed by limitation and loss. Older adults are often portrayed as fragile or disconnected, rather than as the vibrant, experienced, and resilient individuals they are. “Flipping the script” means pushing back against those narrow images and showcasing the full, diverse range of experiences older adults embody—from lifelong learning and professional achievements to leadership in community activism, artistic expression, and innovation.

At Sage Collective®, we see older African Americans especially as cultural stewards, historians, advocates, and everyday heroes whose wisdom and contributions continue to shape our communities. This month, we celebrate the truth: aging is not a story of endings, but of new beginnings and endless possibilities.

Embracing Intergenerational Connections
An important part of flipping the script involves fostering stronger intergenerational relationships. A recent episode of The Atlantic’s podcast, “How to Age Up Together,” explored how communities benefit when older and younger generations collaborate and connect. These relationships not only combat isolation among older adults but also offer younger people valuable mentorship, perspective, and emotional support.

Simple acts — like attending community events together, storytelling across generations, or partnering on volunteer projects — strengthen the social fabric. By encouraging these connections, we can break down age-based silos and build richer, more compassionate communities.

Celebrating Contributions and Promoting Engagement
Throughout May, communities nationwide will honor the accomplishments of older Americans through a variety of creative initiatives: art shows featuring older artists, storytelling festivals where seniors share their life journeys, and wellness fairs focused on active aging.

At Sage Collective®, we encourage older adults to see themselves as lifelong contributors — and to seek out opportunities for engagement that fuel passion and purpose. Whether it’s mentoring a young entrepreneur, joining a new class through our Vibrant Learning Series, or participating in civic leadership, there is no limit to what older adults can achieve and inspire.

How You Can Flip the Script
Everyone has a role to play in shifting the narrative around aging. Here are a few ways you can get involved:

  • Engage in Intergenerational Activities: Organize or join programs that connect people of different ages. Book clubs, dance classes, or mentorship programs are great ways to bridge generational gaps.
  • Highlight Positive Aging Stories: Use social media, community newsletters, or neighborhood events to spotlight older adults living vibrant, impactful lives.
  • Promote Lifelong Learning: Encourage friends and loved ones to explore new hobbies, pursue further education, or share their skills and wisdom with others.
  • Advocate for Inclusion: Support policies and initiatives that make communities more inclusive and accessible for older adults, ensuring they remain connected and empowered.

Moving Forward Together
At Sage Collective®, we are proud to stand at the forefront of a movement that celebrates aging as a source of strength and wisdom. This Older Americans Month, and every day, we reaffirm our commitment to uplifting older African Americans by amplifying their voices, supporting their dreams, and honoring their legacies.

Together, we can “flip the script” — and in doing so, inspire a new, more vibrant vision of what it means to grow older.

For more information and resources on Older Americans Month 2025, visit the ACL’s official page.

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